Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties

Over-expressed in numerous cancers, Ubiquitin-like containing PHD Ring Finger 1 (UHRF1, also known as ICBP90 or Np95) is characterized by a SRA domain (Set and Ring Associated) which is found only in the UHRF family. UHRF1 constitutes a complex with histone deacetylase 1 (HDAC1) and DNA methyltransf...

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Detalhes bibliográficos
Main Authors: Alhosin, Mahmoud, Sharif, Tanveer, Mousli, Marc, Etienne-Selloum, Nelly, Fuhrmann, Guy, Schini-Kerth, Valérie B, Bronner, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096999/
https://ncbi.nlm.nih.gov/pubmed/21496237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-41
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