Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen

Virus infection, such as hepatitis B virus (HBV), occasionally causes endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is counteractive machinery to ER stress, and the failure of UPR to cope with ER stress results in cell death. Mechanisms that regulate the balance between ER s...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Baudi, Ian, Isogawa, Masanori, Moalli, Federica, Onishi, Masaya, Kawashima, Keigo, Ishida, Yuji, Tateno, Chise, Sato, Yusuke, Harashima, Hideyoshi, Ito, Hiroyasu, Ishikawa, Tetsuya, Wakita, Takaji, Iannacone, Matteo, Tanaka, Yasuhito
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143404/
https://ncbi.nlm.nih.gov/pubmed/33979382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009228
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