Type I Interferon Signaling Prevents Hepatitis B Virus-Specific T Cell Responses by Reducing Antigen Expression

Robust virus-specific CD8(+) T cell responses are required for the clearance of hepatitis B virus (HBV). However, the factors that determine the magnitude of HBV-specific CD8(+) T cell responses are poorly understood. To examine the impact of genetic variations of HBV on HBV-specific CD8(+) T cell r...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Kawashima, Keigo, Isogawa, Masanori, Hamada-Tsutsumi, Susumu, Baudi, Ian, Saito, Satoru, Nakajima, Atsushi, Tanaka, Yasuhito
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232490/
https://ncbi.nlm.nih.gov/pubmed/30209178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01099-18
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