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Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic

During the last decades, a continuous rise of multi-drug resistant pathogens has threatened antibiotic efficacy. To tackle this key challenge, novel antimicrobial therapies are needed with increased specificity for the site of infection. Photopharmacology could enable such specificity by allowing fo...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Lauxen, Anna I., Kobauri, Piermichele, Wegener, Michael, Hansen, Mickel J., Galenkamp, Nicole S., Maglia, Giovanni, Szymanski, Wiktor, Feringa, Ben L., Kuipers, Oscar P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143356/
https://ncbi.nlm.nih.gov/pubmed/33919397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050392
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