Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis

CTSD/CathD/CATD (cathepsin D) is a lysosomal aspartic protease. A distinguishing characteristic of CTSD is its dual functions of promoting cell proliferation via secreting a pro-enzyme outside the cells as a ligand, and promoting apoptosis via the mature form of this enzyme inside cells; however, th...

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Foilsithe in:Autophagy
Main Authors: Di, Yu-Qin, Han, Xiao-Lin, Kang, Xin-Le, Wang, Di, Chen, Cai-Hua, Wang, Jin-Xing, Zhao, Xiao-Fan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2020
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143247/
https://ncbi.nlm.nih.gov/pubmed/32324083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1752497
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