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Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis
CTSD/CathD/CATD (cathepsin D) is a lysosomal aspartic protease. A distinguishing characteristic of CTSD is its dual functions of promoting cell proliferation via secreting a pro-enzyme outside the cells as a ligand, and promoting apoptosis via the mature form of this enzyme inside cells; however, th...
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| Pubblicato in: | Autophagy |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8143247/ https://ncbi.nlm.nih.gov/pubmed/32324083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1752497 |
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