Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons

Tau aggregation within neurons is a critical feature of Alzheimer's disease (AD) and related tauopathies. It is believed that soluble pathologic tau species seed the formation of tau aggregates in a prion-like manner and propagate through connected neurons during the progression of disease. Bot...

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Vydáno v:J Neurosci
Hlavní autoři: Oakley, Derek H., Klickstein, Naomi, Commins, Caitlin, Chung, Mirra, Dujardin, Simon, Bennett, Rachel E., Hyman, Bradley T., Frosch, Matthew P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143197/
https://ncbi.nlm.nih.gov/pubmed/33893219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2590-20.2021
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