Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity

Cancer cells function as primary architects of the tumor microenvironment. However, the molecular features of cancer cells that govern stromal cell phenotypes remain unclear. Here, we show that cancer-associated fibroblast (CAF) heterogeneity is driven by lung adenocarcinoma (LUAD) cells at either e...

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Pubblicato in:Cell Rep
Autori principali: Bota-Rabassedas, Neus, Banerjee, Priyam, Niu, Yichi, Cao, Wenjian, Luo, Jiayi, Xi, Yuanxin, Tan, Xiaochao, Sheng, Kuanwei, Ahn, Young-Ho, Lee, Sieun, Parra, Edwin Roger, Rodriguez-Canales, Jaime, Albritton, Jacob, Weiger, Michael, Liu, Xin, Guo, Hou-Fu, Yu, Jiang, Rodriguez, B. Leticia, Firestone, Joshua J.A., Mino, Barbara, Creighton, Chad J., Solis, Luisa M., Villalobos, Pamela, Raso, Maria Gabriela, Sazer, Daniel W., Gibbons, Don L., Russell, William K., Longmore, Gregory D., Wistuba, Ignacio I., Wang, Jing, Chapman, Harold A., Miller, Jordan S., Zong, Chenghang, Kurie, Jonathan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142261/
https://ncbi.nlm.nih.gov/pubmed/33882319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109009
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