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A local-neighborhood Lassen plot filter for creating occupancy and non-displaceable binding images

For radioligands without a reference region, the Lassen plot can be used to estimate receptor occupancy by an exogenous drug ([Formula: see text]). However, the Lassen plot is not well-suited for spatial variation in [Formula: see text]. To overcome this limitation, we introduce a Lassen plot filter...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: de Laat, Bart, Morris, Evan D.
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142134/
https://ncbi.nlm.nih.gov/pubmed/33050827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20950486
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