The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis

Epigenetic regulation disorder is important in the onset and pathogenesis of inflammatory bowel disease (IBD). SETD2, a trimethyltransferase of histone H3K36, is frequently mutated in IBD samples with a high risk of developing colorectal cancer (CRC). However, functions of SETD2 in IBD and colitis-a...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Liu, Min, Rao, Hanyu, Liu, Jing, Li, Xiaoxue, Feng, Wenxin, Gui, Liming, Tang, Huayuan, Xu, Jin, Gao, Wei-Qiang, Li, Li
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141928/
https://ncbi.nlm.nih.gov/pubmed/34020310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102004
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