Peptide: MHC-based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors

BACKGROUND: Natural killer (NK) cells are increasingly being recognized as agents for cancer immunotherapy. The killer cell immunoglobulin-like receptors (KIRs) are expressed by NK cells and are immunogenetic determinants of the outcome of cancer. In particular, KIR2DS2 is associated with protective...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Rettman, Pauline, Blunt, Matthew D, Fulton, Rebecca J, Vallejo, Andres F, Bastidas-Legarda, Leidy Y, España-Serrano, Laura, Polak, Marta E, Al-Shamkhani, Aymen, Retiere, Christelle, Khakoo, Salim I
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Immune Cell Therapies and Immune Cell Engineering
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141441/
https://ncbi.nlm.nih.gov/pubmed/34016721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001912
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