Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis

Natural killer (NK) cells are innate immune cells that interface with the adaptive immune system to generate a pro-inflammatory immune environment. Primary Biliary Cholangitis (PBC) is a hepatic autoimmune disorder with extrahepatic associations including systemic sclerosis, Sjogren's syndrome...

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Main Authors: Theresa J. Hydes, Matthew D. Blunt, Jennifer Naftel, Andres F. Vallejo, Grégory Seumois, Alice Wang, Pandurangan Vijayanand, Marta E. Polak, Salim I. Khakoo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-11-01
Colecção:Frontiers in Immunology
Assuntos:
primary biliary cholangitis
natural killer cells
chemokine receptor 6 protein
human
interleukin-12
STAT4 transcription factor
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.02633/full
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