Cryoprecipitate Attenuates the Endotheliopathy of Trauma in Mice Subjected to Hemorrhagic Shock and Trauma

BACKGROUND: Plasma has been shown to mitigate the endotheliopathy of trauma (EOT). Protection of the endothelium may be due in part to fibrinogen and other plasma-derived proteins found in cryoprecipitate, however the exact mechanisms remain unknown. Clinical trials are underway investigating early...

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Udgivet i:J Trauma Acute Care Surg
Main Authors: Barry, Mark, Trivedi, Alpa, Miyazawa, Byron Y., Vivona, Lindsay R., Khakoo, Manisha, Zhang, Haoqian, Pathipati, Praneeti, Bagri, Anil, Gatmaitan, Michelle G., Kozar, Rosemary, Stein, Deborah, Pati, Shibani
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141010/
https://ncbi.nlm.nih.gov/pubmed/33797484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000003164
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