Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Pulmonary Vascular Permeability and Lung Injury Induced by Hemorrhagic Shock and Trauma

BACKGROUND: Mesenchymal stem cells (MSCs) have been shown to mitigate vascular permeability in hemorrhagic shock (HS) and trauma-induced brain and lung injury. Mechanistically, paracrine factors secreted from MSCs have been identified that can recapitulate many of the potent biologic effects of MSCs...

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Publicado en:J Trauma Acute Care Surg
Main Authors: Potter, Daniel R., Miyazawa, Byron Y., Gibb, Stuart L., Deng, Xutao, Togaratti, Padma P., Croze, Roxanne H., Srivastava, Amit K., Trivedi, Alpa, Matthay, Michael, Holcomb, John B., Schreiber, Martin A., Pati, Shibani
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378956/
https://ncbi.nlm.nih.gov/pubmed/29251710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001744
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