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MiR-21-5p in Macrophage-Derived Exosomes Targets Smad7 to Promote Epithelial Mesenchymal Transition of Airway Epithelial Cells

BACKGROUND: Asthma is usually associated with airway inflammation and airway remodeling. Epithelial mesenchymal transition (EMT) often occurs in airway remodeling. The purpose of this study is to identify the effect of miR-21-5p and Smad7 signaling pathway in macrophage-derived exosomes on EMT of ai...

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Detalhes bibliográficos
Publicado no:J Asthma Allergy
Main Authors: Li, Xiang, Yang, Nan, Cheng, Qi, Zhang, Han, Liu, Fen, Shang, Yunxiao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140948/
https://ncbi.nlm.nih.gov/pubmed/34040396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JAA.S307165
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