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MiR-21-5p in Macrophage-Derived Exosomes Targets Smad7 to Promote Epithelial Mesenchymal Transition of Airway Epithelial Cells

BACKGROUND: Asthma is usually associated with airway inflammation and airway remodeling. Epithelial mesenchymal transition (EMT) often occurs in airway remodeling. The purpose of this study is to identify the effect of miR-21-5p and Smad7 signaling pathway in macrophage-derived exosomes on EMT of ai...

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Podrobná bibliografie
Vydáno v:J Asthma Allergy
Hlavní autoři: Li, Xiang, Yang, Nan, Cheng, Qi, Zhang, Han, Liu, Fen, Shang, Yunxiao
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140948/
https://ncbi.nlm.nih.gov/pubmed/34040396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JAA.S307165
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