Follicular dendritic cell activation by TLR ligands promotes autoreactive B cell responses

A hallmark of autoimmunity in murine models of lupus is the formation of germinal centers (GC) in lymphoid tissues where self-reactive B cells expand and differentiate. In the host response to foreign antigens, follicular dendritic cells (FDCs) are essential for the maintenance of GCs through their...

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Udgivet i:Immunity
Main Authors: Das, Abhishek, Heesters, Balthasar A., Bialas, Allison, O’Flynn, Joseph, Rifkin, Ian R., Ochando, Jordi, Mittereder, Nanette, Carlesso, Gianluca, Herbst, Ronald, Carroll, Michael C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140609/
https://ncbi.nlm.nih.gov/pubmed/28099860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.12.014
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