Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling

Testosterone (T) reduces male fat mass, but the underlying mechanisms remain elusive, limiting its clinical relevance in hypogonadism-associated obesity. Here, we subjected chemically castrated high-fat diet–induced adult obese male mice to supplementation with T or the nonaromatizable androgen dihy...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Kim, Na Ri, David, Karel, Corbeels, Katrien, Khalil, Rougin, Antonio, Leen, Schollaert, Dieter, Deboel, Ludo, Ohlsson, Claes, Gustafsson, Jan-Åke, Vangoitsenhoven, Roman, Van der Schueren, Bart, Decallonne, Brigitte, Claessens, Frank, Vanderschueren, Dirk, Dubois, Vanessa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140602/
https://ncbi.nlm.nih.gov/pubmed/33674833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab045
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