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Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids

Stem cell technologies including self-assembling 3D tissue models provide access to early human neurodevelopment and fundamental insights into neuropathologies. Gastruloid models have not been used to investigate co-developing central and peripheral neuronal systems with trunk mesendoderm which we a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Olmsted, Zachary T., Paluh, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140076/
https://ncbi.nlm.nih.gov/pubmed/34021144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23294-7
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