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Brain selective estrogen treatment protects dopaminergic neurons and preserves behavioral function in MPTP-induced mouse model of Parkinson’s disease

Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra and loss of both motor and non-motor features. Several clinical and preclinical studies have provided evidence that estrogen therapy reduces the risk of PD but have limitations in te...

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Bibliographische Detailangaben
Veröffentlicht in:J Neuroimmune Pharmacol
Hauptverfasser: Thadathil, Nidheesh, Xiao, Jianfeng, Hori, Roderick, Alway, Stephen E., Khan, Mohammad Moshahid
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140060/
https://ncbi.nlm.nih.gov/pubmed/33221984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-020-09972-1
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