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Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells

The developmental origins of mesenchymal progenitor cells (MPCs) and molecular machineries regulating their fate and differentiation are far from defined owing to their complexity. Osteoblasts and adipocytes are descended from common MPCs. Their fates are collectively determined by an orchestra of p...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Zhou, Xin, Beilter, Allyson, Xu, Zhaohui, Gao, Ruli, Xiong, Shunbin, Paulucci-Holthauzen, Adriana, Lozano, Guillermina, de Crombrugghe, Benoit, Gorlick, Richard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139956/
https://ncbi.nlm.nih.gov/pubmed/34021120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03758-w
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