Host Serine Proteases TMPRSS2 and TMPRSS11D Mediate Proteolytic Activation and Trypsin-Independent Infection in Group A Rotaviruses

Group A rotaviruses (RVAs) are representative enteric virus species and major causes of diarrhea in humans and animals. The RVA virion is a triple-layered particle, and the outermost layer consists of the glycoprotein VP7 and spike protein VP4. To increase the infectivity of RVA, VP4 is proteolytica...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Sasaki, Michihito, Itakura, Yukari, Kishimoto, Mai, Tabata, Koshiro, Uemura, Kentaro, Ito, Naoto, Sugiyama, Makoto, Wastika, Christida E., Orba, Yasuko, Sawa, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139689/
https://ncbi.nlm.nih.gov/pubmed/33762412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00398-21
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