An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel

BACKGROUND: The amino acid sequence of proteins generally carries all the necessary information for acquisition of native conformations, but the vectorial nature of translation can additionally determine the folding outcome. Such consideration is particularly relevant in human diseases associated to...

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Detaylı Bibliyografya
Yayımlandı:BMC Biol
Asıl Yazarlar: Urrutia, Janire, Aguado, Alejandra, Gomis-Perez, Carolina, Muguruza-Montero, Arantza, Ballesteros, Oscar R., Zhang, Jiaren, Nuñez, Eider, Malo, Covadonga, Chung, Hee Jung, Leonardo, Aritz, Bergara, Aitor, Villarroel, Alvaro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138981/
https://ncbi.nlm.nih.gov/pubmed/34020651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-01040-1
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