LKB1 mutations in NSCLC are associated with KEAP1/NRF2-dependent radiotherapy resistance targetable by glutaminase inhibition

PURPOSE: Radiotherapy (RT) with or without chemotherapy is a mainstay of treatment for locally advanced non-small cell lung cancer (NSCLC), but no predictive markers are currently available to select patients who will benefit from these therapies. In this study we investigated the association betwee...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Sitthideatphaiboon, Piyada, Galan-Cobo, Ana, Negrao, Marcelo V., Qu, Xiao, Poteete, Alissa, Zhang, Fahao, Liu, Diane D., Lewis, Whitney E., Kemp, Haley N., Lewis, Jeff, Rinsurongkawong, Waree, Giri, Uma, Lee, J. Jack, Zhang, Jianjun, Roth, Jack A., Swisher, Stephen, Heymach, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138942/
https://ncbi.nlm.nih.gov/pubmed/33323404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2859
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados