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Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair
Radiation is widely used for cancer treatment but the radioresistance properties of cancer stem cells (CSCs) pose a significant challenge to the success of cancer therapy. Nuclear factor erythroid-2-related factor 2 (Nrf2) has emerged as a prominent regulator of cellular antioxidant responses and it...
Shranjeno v:
| izdano v: | Free Radic Biol Med |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138866/ https://ncbi.nlm.nih.gov/pubmed/33892113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2021.04.006 |
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