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Insulin-like growth factor-2 regulates basal retinal insulin receptor activity

The retinal insulin receptor (IR) exhibits basal kinase activity equivalent to that of the liver of fed animals, but unlike the liver, does not fluctuate with feeding and fasting; it also declines rapidly after the onset of insulin-deficient diabetes. The ligand(s) that determine basal IR activity i...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Zolov, Sergey N., Imai, Hisanori, Losiewicz, Mandy K., Singh, Ravi S.J., Fort, Patrice E., Gardner, Thomas W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138762/
https://ncbi.nlm.nih.gov/pubmed/33915127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100712
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