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Insulin-like growth factor-2 regulates basal retinal insulin receptor activity

The retinal insulin receptor (IR) exhibits basal kinase activity equivalent to that of the liver of fed animals, but unlike the liver, does not fluctuate with feeding and fasting; it also declines rapidly after the onset of insulin-deficient diabetes. The ligand(s) that determine basal IR activity i...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zolov, Sergey N., Imai, Hisanori, Losiewicz, Mandy K., Singh, Ravi S.J., Fort, Patrice E., Gardner, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138762/
https://ncbi.nlm.nih.gov/pubmed/33915127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100712
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