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Crystal structures of inhibitor complexes of M‐PMV protease with visible flap loops

Mason‐Pfizer monkey virus protease (PR) was crystallized in complex with two pepstatin‐based inhibitors in P1 space group. In both crystal structures, the extended flap loops that lock the inhibitor/substrate over the active site, are visible in the electron density either completely or with only sm...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Wosicki, Stanislaw, Kazmierczyk, Maciej, Gilski, Miroslaw, Zabranska, Helena, Pichova, Iva, Jaskolski, Mariusz
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138519/
https://ncbi.nlm.nih.gov/pubmed/33786913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4072
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