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Crystal structures of inhibitor complexes of M‐PMV protease with visible flap loops

Mason‐Pfizer monkey virus protease (PR) was crystallized in complex with two pepstatin‐based inhibitors in P1 space group. In both crystal structures, the extended flap loops that lock the inhibitor/substrate over the active site, are visible in the electron density either completely or with only sm...

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書目詳細資料
發表在:Protein Sci
Main Authors: Wosicki, Stanislaw, Kazmierczyk, Maciej, Gilski, Miroslaw, Zabranska, Helena, Pichova, Iva, Jaskolski, Mariusz
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Inc. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138519/
https://ncbi.nlm.nih.gov/pubmed/33786913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4072
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