Oxaliplatin-Induced Neuropathy: Genetic and Epigenetic Profile to Better Understand How to Ameliorate This Side Effect

In the most recent decades, oxaliplatin has been used as a chemotherapeutic agent for colorectal cancer and other malignancies as well. Oxaliplatin interferes with tumor growth predominantly exerting its action in DNA synthesis inhibition by the formation of DNA-platinum adducts that, in turn, leads...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Principais autores: Branca, Jacopo Junio Valerio, Carrino, Donatello, Gulisano, Massimo, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Pacini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138476/
https://ncbi.nlm.nih.gov/pubmed/34026827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.643824
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