Oxaliplatin-induced blood brain barrier loosening: a new point of view on chemotherapy-induced neurotoxicity

Oxaliplatin is a key drug in the treatment of advanced metastatic colorectal cancer. Despite its beneficial effects in tumor reduction, the most prevalent side-effect of oxaliplatin treatment is a chemotherapy-induced neuropathy that frequently forces to discontinue the therapy. Indeed, along with d...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Branca, Jacopo Junio Valerio, Maresca, Mario, Morucci, Gabriele, Becatti, Matteo, Paternostro, Ferdinando, Gulisano, Massimo, Ghelardini, Carla, Salvemini, Daniela, Di Cesare Mannelli, Lorenzo, Pacini, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955120/
https://ncbi.nlm.nih.gov/pubmed/29805744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25193
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