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Intracellular versus extracellular inhibition of calpain I causes differential effects on pain in a rat model of joint inflammation
Calpain I is a calcium-dependent cysteine protease which has dual effects on tissue inflammation depending on its cellular location. Intracellularly, calpain I has pro-inflammatory properties but becomes anti-inflammatory when exteriorised into the extracellular space. In this study, the effect of c...
Enregistré dans:
| Publié dans: | Mol Pain |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
SAGE Publications
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138287/ https://ncbi.nlm.nih.gov/pubmed/34006144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/17448069211016141 |
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