Opposite alterations of 5­HT(2A) receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile

The status of serotonin 5­HT(2A) receptors (5­HT(2A)Rs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about 5­HT(2A)R density. Radiotracers bind different receptor conformations de...

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Publicado no:Transl Psychiatry
Main Authors: Diez-Alarcia, Rebeca, Muguruza, Carolina, Rivero, Guadalupe, García-Bea, Aintzane, Gómez-Vallejo, Vanessa, Callado, Luis F., Llop, Jordi, Martín, Abraham, Meana, J. Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137947/
https://ncbi.nlm.nih.gov/pubmed/34016955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01430-7
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