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In Vitro Effects of 5-Lipoxygenase Pathway Inhibition on Rhinovirus-Associated Bronchial Epithelial Inflammation

INTRODUCTION: The leukotriene pathway may be implicated in the induction of virus-induced inflammation. Respiratory epithelial cells may express low levels of 5-lipoxygenase (5-LO) and release leukotrienes (LTs) C4, D4, and E4, upon exposure to viruses or other stimuli. Enhanced expression of 5-LO p...

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Bibliografische gegevens
Gepubliceerd in:Pulm Ther
Hoofdauteurs: Spyridaki, Irini, Taka, Styliani, Skevaki, Chrysanthi, Trochoutsou, Aikaterini, Papadopoulos, Nikolaos G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Healthcare 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137792/
https://ncbi.nlm.nih.gov/pubmed/33847974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s41030-021-00152-x
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