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In Vitro Effects of 5-Lipoxygenase Pathway Inhibition on Rhinovirus-Associated Bronchial Epithelial Inflammation

INTRODUCTION: The leukotriene pathway may be implicated in the induction of virus-induced inflammation. Respiratory epithelial cells may express low levels of 5-lipoxygenase (5-LO) and release leukotrienes (LTs) C4, D4, and E4, upon exposure to viruses or other stimuli. Enhanced expression of 5-LO p...

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Detalhes bibliográficos
Publicado no:Pulm Ther
Main Authors: Spyridaki, Irini, Taka, Styliani, Skevaki, Chrysanthi, Trochoutsou, Aikaterini, Papadopoulos, Nikolaos G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137792/
https://ncbi.nlm.nih.gov/pubmed/33847974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s41030-021-00152-x
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