Constitutive activation of CTNNB1 results in a loss of spermatogonial stem cell activity in mice

Spermatogenesis requires that a careful balance be maintained between the self-renewal of spermatogonial stem cells (SSCs) and their commitment to the developmental pathway through which they will differentiate into spermatozoa. Recently, a series of studies employing various in vivo and in vitro mo...

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Udgivet i:PLoS One
Main Authors: Boyer, Alexandre, Zhang, Xiangfan, Levasseur, Adrien, Abou Nader, Nour, St-Jean, Guillaume, Nagano, Makoto C., Boerboom, Derek
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136708/
https://ncbi.nlm.nih.gov/pubmed/34015032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251911
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