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Constitutive activation of CTNNB1 results in a loss of spermatogonial stem cell activity in mice

Spermatogenesis requires that a careful balance be maintained between the self-renewal of spermatogonial stem cells (SSCs) and their commitment to the developmental pathway through which they will differentiate into spermatozoa. Recently, a series of studies employing various in vivo and in vitro mo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Boyer, Alexandre, Zhang, Xiangfan, Levasseur, Adrien, Abou Nader, Nour, St-Jean, Guillaume, Nagano, Makoto C., Boerboom, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136708/
https://ncbi.nlm.nih.gov/pubmed/34015032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251911
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