Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation

Phospholipase D (PLD) is an enzyme useful for the enzymatic modification of phospholipids. In the presence of primary alcohols, the enzyme catalyses transphosphatidylation of the head group of phospholipid substrates to synthesise a modified phospholipid product. However, the enzyme is specific for...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem J
Prif Awduron: Samantha, Ariela, Damnjanović, Jasmina, Iwasaki, Yugo, Nakano, Hideo, Vrielink, Alice
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2021
Pynciau:
Structural Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133832/
https://ncbi.nlm.nih.gov/pubmed/33843991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210117
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg