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Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation

Phospholipase D (PLD) is an enzyme useful for the enzymatic modification of phospholipids. In the presence of primary alcohols, the enzyme catalyses transphosphatidylation of the head group of phospholipid substrates to synthesise a modified phospholipid product. However, the enzyme is specific for...

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Detaylı Bibliyografya
Yayımlandı:Biochem J
Asıl Yazarlar: Samantha, Ariela, Damnjanović, Jasmina, Iwasaki, Yugo, Nakano, Hideo, Vrielink, Alice
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133832/
https://ncbi.nlm.nih.gov/pubmed/33843991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210117
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