Weighting tumor-specific TCR repertoires as a classifier to stratify the immunotherapy delivery in non–small cell lung cancers

Analysis of T cell receptor (TCR) repertoires may contribute to better understanding of the response to immunotherapy. By deep sequencing of the TCR β chain complementarity-determining regions in the paired biopsies and peripheral blood specimens of 31 patients with non–small cell lung cancer (NSCLC...

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Vydáno v:Sci Adv
Hlavní autoři: Han, Jiefei, Yu, Ruofei, Duan, Jianchun, Li, Jin, Zhao, Wei, Feng, Guoshuang, Bai, Hua, Wang, Yuqi, Zhang, Xue, Wan, Rui, Xu, Jiachen, Wang, Xin, Guan, Yanfang, Xia, Xuefeng, Yao, Zhuoran, Fei, Kailun, Carbone, David P., Wang, Zhijie, Wang, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133747/
https://ncbi.nlm.nih.gov/pubmed/34138742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6971
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