Mesenchymal stromal cell delivery via an ex vivo bioreactor preclinical test system attenuates clot formation for intravascular application

While mesenchymal stromal cells are an appealing therapeutic option for a range of clinical applications, their potential to induce clotting when used systemically remains a safety concern, particularly in hypercoagulable conditions, such as in patients with severe COVID‐19, trauma, or cancers. Here...

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Pubblicato in:Stem Cells Transl Med
Autori principali: O'Rourke, Brian, Nguyen, Sunny, Tilles, Arno W., Bynum, James A., Cap, Andrew P., Parekkadan, Biju, Barcia, Rita N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2021
Soggetti:
Enabling Technologies for Cell‐based Clinical Translation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133341/
https://ncbi.nlm.nih.gov/pubmed/33527780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0454
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