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Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

Bone marrow mesenchymal stromal cells (MSCs) have been studied for decades as potent immunomodulators. Clinically, they have shown some promise but with limited success. Here, we report the ability of a scalable hollow fiber bioreactor to effectively maintain ideal MSC function as a single populatio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Allen, Ashley, Vaninov, Natalie, Li, Matthew, Nguyen, Sunny, Igo, Peter, Tilles, Arno W., O’Rourke, Brian, Miller, Brian L. K., Parekkadan, Biju, Barcia, Rita N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311545/
https://ncbi.nlm.nih.gov/pubmed/32576889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67039-w
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