Probing the mechanism for hydrogel-based stasis induction in human pluripotent stem cells: is the chemical functionality of the hydrogel important?

It is well-known that pluripotent human embryonic stem cells (hPSC) can differentiate into any cell type. Recently, we reported that hPSC colonies enter stasis when immersed in an extremely soft hydrogel comprising hydroxyl-functional block copolymer worms (I. Canton, N. J. Warren, A. Chahal, K. Amp...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Sponchioni, M., O'Brien, C. T., Borchers, C., Wang, E., Rivolta, M. N., Penfold, N. J. W., Canton, I., Armes, S. P.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society of Chemistry 2019
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133024/
https://ncbi.nlm.nih.gov/pubmed/34040716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04734d
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