Liver development is restored by blastocyst complementation of HHEX knockout in mice and pigs

BACKGROUND: There are over 17,000 patients in the US waiting to receive liver transplants, and these numbers are increasing dramatically. Significant effort is being made to obtain functional hepatocytes and liver tissue that can for therapeutic use in patients. Blastocyst complementation is a chall...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Ruiz-Estevez, M., Crane, A. T., Rodriguez-Villamil, P., Ongaratto, F. L., You, Yun, Steevens, A. R., Hill, C., Goldsmith, T., Webster, D. A., Sherry, L., Lim, S., Denman, N., Low, W. C., Carlson, D. F., Dutton, J. R., Steer, C. J., Gafni, O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132445/
https://ncbi.nlm.nih.gov/pubmed/34011403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02348-z
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