Generation of inner ear sensory neurons using blastocyst complementation in a Neurog1(+/−)−deficient mouse

This research is the first to produce induced pluripotent stem cell-derived inner ear sensory neurons in the Neurog1(+/−) heterozygote mouse using blastocyst complementation. Additionally, this approach corrected non-sensory deficits associated with Neurog1 heterozygosity, indicating that complement...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Steevens, Aleta R., Griesbach, Matthew W., You, Yun, Dutton, James R., Low, Walter C., Santi, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881691/
https://ncbi.nlm.nih.gov/pubmed/33579352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02184-1
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