mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status

While mRNA vaccines are proving highly efficacious against SARS-CoV-2, it is important to determine how booster doses and prior infection influence the immune defense they elicit, and whether they protect against variants. Focusing on the T cell response, we conducted a longitudinal study of infecti...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Neidleman, Jason, Luo, Xiaoyu, McGregor, Matthew, Xie, Guorui, Murray, Victoria, Greene, Warner C., Lee, Sulggi A., Roan, Nadia R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132283/
https://ncbi.nlm.nih.gov/pubmed/34013277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.12.443888
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