SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential

Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defined. Using 38-parameter CyTOF, we phenotyped longitudinal s...

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Bibliographic Details
Published in:Cell Rep Med
Main Authors: Neidleman, Jason, Luo, Xiaoyu, Frouard, Julie, Xie, Guorui, Gill, Gurjot, Stein, Ellen S., McGregor, Matthew, Ma, Tongcui, George, Ashley F., Kosters, Astrid, Greene, Warner C., Vasquez, Joshua, Ghosn, Eliver, Lee, Sulggi, Roan, Nadia R.
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437502/
https://ncbi.nlm.nih.gov/pubmed/32839763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100081
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