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Short sequence motif dynamics in the SARS-CoV-2 genome suggest a role for cytosine deamination in CpG reduction

RNA viruses use CpG reduction to evade the host cell defense, but the driving mechanisms are still largely unknown. In an attempt to address this we used a rapidly growing genomic dataset of SARS-CoV-2 with relevant metadata information. Remarkably, by simply ordering SARS-CoV-2 genomes by their dat...

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Publicat a:bioRxiv
Autors principals: Sadykov, Mukhtar, Mourier, Tobias, Guan, Qingtian, Pain, Arnab
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132218/
https://ncbi.nlm.nih.gov/pubmed/34013262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.19.161687
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