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Cytosine deamination and selection of CpG suppressed clones are the two major independent biological forces that shape codon usage bias in coronaviruses

Using the complete genome sequences of 19 coronavirus genomes, we analyzed the codon usage bias, dinucleotide relative abundance and cytosine deamination in coronavirus genomes. Of the eight codons that contain CpG, six were markedly suppressed. The mean NNU/NNC ratio of the six amino acids using ei...

詳細記述

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書誌詳細
出版年:Virology
主要な著者: Woo, Patrick C.Y., Wong, Beatrice H.L., Huang, Yi, Lau, Susanna K.P., Yuen, Kwok-Yung
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Inc. 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103290/
https://ncbi.nlm.nih.gov/pubmed/17881030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.010
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