Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species

Sarbecovirus (CoV) infections, including Severe Acute Respiratory CoV (SARS-CoV) and SARS-CoV-2, are considerable human threats. Human GWAS studies have recently identified loci associated with variation in SARS-CoV-2 susceptibility. However, genetically tractable models that reproduce human CoV dis...

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Publicado no:bioRxiv
Principais autores: Schäfer, Alexandra, Gralinski, Lisa E., Leist, Sarah R., Winkler, Emma S., Hampton, Brea K., Mooney, Michael A., Jensen, Kara L., Graham, Rachel L., Agnihothram, Sudhakar, Jeng, Sophia, Chamberlin, Steven, Bell, Timothy A., Scobey, D. Trevor, VanBlargan, Laura A., Thackray, Larissa B., Hock, Pablo, Miller, Darla R., Shaw, Ginger D., de Villena, Fernando Pardo Manuel, McWeeney, Shannon K., Montgomery, Stephanie A., Diamond, Michael S., Heise, Mark T., Menachery, Vineet D., Ferris, Martin T., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132217/
https://ncbi.nlm.nih.gov/pubmed/34013261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.14.444205
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